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How Can Preimplantation Genetic Testing Help My Patients?

Preimplantation Genetic Testing (PGT) performed in conjunction with an IVF cycle will help ensure the embryo selected for transfer will not have the genotype conferring the single gene or chromosomal abnormality tested. This will:

Avoid Pregnancies with Chromosomal Abnormalities and Genetic Conditions
Increase Implantation Rate
Reduce the Likelihood of Miscarriage
Identify a Single Euploid Embryo (Single Embryo Transfer (SET)), to avoid multiple embryos with increased risk
Avoids transfer of an embryo affected by specific single gene disorder(s)
Allow for transfer of HLA matched embryo
Our Tests

Preimplantation Genetic Testing for Aneuploidy (PGT-A)

RGI is a recognized leader in the field of assisted reproductive technologies and has performed Preimplantation Genetic Testing (PGT) for thousands of families all over the world.

PGT-A determines if an embryo contains the normal number of chromosomes prior to pregnancy, transfer of which can optimize the success of an In Vitro Fertilization (IVF) cycle and reduce the chance of miscarriage.

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Preimplantation Genetic Testing for Monogenic / Single Gene Conditions (PGT-M)

PGT-M detects genetic conditions prior to pregnancy, including autosomal dominant, recessive, X-linked, and de novo conditions, which can help at-risk couples have children free of their family’s genetic diseases.

PGT-M allows for selection of embryos free of genetic disorder, while avoiding the difficult decision about the outcome of a pregnancy following abnormal prenatal test results. RGI tests for rare conditions, offering specific test set-ups not available at other labs.

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Preimplantation Genetic Testing for Structural Rearrangements (PGT-SR)

PGT-SR identifies structural chromosomal abnormalities caused by rearrangements, including translocations, inversions, deletions and duplications, prior to achievement of a pregnancy.

PGT-SR allows for a viable pregnancy, reducing or avoiding the chance of a failed implantation, miscarriage and/or the birth of a child with congenital anomalies, resulting from an unbalanced chromosome translocation.

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Preimplantation Genetic Testing Human Leukocyte Antigen (PGT-HLA)

PGT-HLA identifies embryos that are HLA compatible with a child who is in need of a bone marrow or cord blood transplant.

PGT-HLA is requested by couples where a previous child is in need of a bone marrow or cord blood transplant due to a genetic disorder. Matching bone marrow or cord blood can be used to treat a sibling affected with certain blood disorders. In planning future pregnancy, not only is it desired to have a child without the disorder, but an HLA-compatible child whose umbilical cord blood can be used for stem cell transplantation, to provide normally functioning bone marrow.

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Reproductive Genetic Innovations offers state-of-the-art technologies to test embryos for many different single Gene Disorders, Aneuploidies, Structural Rearrangements and HLA matching.

Providers Trust RGI for Their Patients

Advanced Maternal Age
Testing Previously Frozen Embryos
Maximizing a Transfer of Successful Donor Oocytes
Prior Pregnancy of Child with a Chromosomal Abnormality
Recurrent Pregnancy Loss
Repeated IVF Failures
Patient Desire to Determine Sex

Reproductive Genetic Innovations

Reproductive Genetic Innovations is an internationally recognized leader in the field of assisted reproductive technologies and has performed Preimplantation Genetic Testing for thousands of families from all over the world. 

With over 30 years of experience and results, our scientists have pioneered many of the techniques for embryo biopsy and preimplantation genetic analysis needed for single gene disorders and HLA matching. Our comprehensive test menu also includes 24-chromosome PGT-A, PGT-SR for chromosomal rearrangements, and POC testing.

As an independently run IVF and Molecular Genetics lab, RGI works with experienced referral doctors to provide the highest quality embryology, genetic, and andrology services. This combined with our unparalleled experience in PGT has helped to make RGI’s laboratories the primary choice for intended parents.

Our laboratories provide services in all aspects of ART: PGT-A, PGT-M, PGT-SR, PGT-HLA, oocyte/embryo culture, insemination (including ICSI), blastocyst culture, embryo transfer, embryo and oocyte vitrification, embryo biopsies, semen analysis, semen and oocyte cryopreservation.

How & When is PGT Performed?

PGT is performed by sampling the developing embryo at different time points in conjunction with an IVF cycle. RGI customizes the testing strategy to obtain the most accurate diagnosis for your patient’s embryos. Their indication will determine which testing option is best for the indication.

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What is the PGT Process?

Our PGT Team of experts develops testing strategies that will be based on your individual patient’s needs and your recommendation.

  • Counseling + Testing Plan Counseling + Testing Plan
  • PGT Set-Up PGT Set-Up
  • IVF + Embryo Biopsy IVF + Embryo Biopsy
  • PGT Testing PGT Testing
  •  Result + Embryo Selection

 

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How Are Embryology Services Arranged?

Have a Laser, but no Embryologist? RGI offers traveling embryology services, we will send a fully qualified embryologist to your facility to perform all types of embryo biopsies and will transport the samples back to RGI for testing
Have an Embryologist, but no Laser for Biopsies? RGI embryologists have mastered the art of a Day-4, mechanical biopsy that does not require the use of a laser.
Interested in Learning More about Mechanical Biopsies? Our embryology team has traveled around the world to provide embryology services, training workshops, and lectures as well as provided training on site at RGI.
Have Frozen Embryos that Need to be Genetically Tested? Send us the frozen embryos and our embryologists will thaw them, perform embryo biopsy, refreeze, and send them back to you.
Need Embryo Storage? RGI provides secure storage and cryopreservation of oocytes, embryos, and semen for thousands of patients in our cryobank.

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How Do I Refer A Patient?

Give your patients the best chance for a healthy child with RGI!

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What Counseling Is Available?

Our certified genetic counselors are available to discuss PGT options with your patients and help guide them every step of the way. Genetic counseling for PGT is included in the cost of testing!

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How Does RGI Make Billing Easier?

Our financial team works directly with patients and clinics to make the process as easy as possible, from benefit verification to claim submission. RGI provides a tailored approach to billing thus making the process easier for your patient and your clinic.

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Why Choose RGI? Reproductive Genetic Innovations is an internationally recognized leader in the field of assisted reproductive technologies and has performed Preimplantation Genetic Testing for thousands of families all over the world.

  • Reliable Results with Optimal Accuracy of 98%
  • Over 30 years of reliable PGT test results
  • Accredited Laboratories
  • PGT-M Performed for Over 650 Single Gene Disorders and counting
  • PGT for Rare, De Novo, and Mosaic Cases
  • Complementary Genetic Counseling for PGT for Patients
  • Customized Testing Strategies for Each Patient
  • Multi-step Independent Result Review Process
  • Competitive Pricing
  • Biopsy training available for IVF Center embryologists
  • In-House IVF Lab

How Do We Get Started?

We welcome the opportunity to work with your center. To get started, complete a Center Registration Form or contact us.

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