Preimplantation Genetic Testing

PGT-M is a genetic testing technique designed to identify if there is a single-gene disorder(s) in embryos created through in vitro fertilization (IVF). These disorders, which include conditions such as cystic fibrosis, sickle cell anemia, and Huntington’s disease, are usually caused by mutations in a single gene. By testing embryos for these genetic abnormalities before implantation, couples can select and transfer only those embryos that are free from the targeted disorder (genetic variant), avoiding the risk of passing it on to their children.

Throughout your pre-implantation testing journey, you might hear terms like PGT-A, PGT-M, PGT-SR, PGT-HLA, NGS, PCR, etc. All these letters can get pretty confusing if you aren’t sure what they mean, so let’s break it down.