Preimplantation Genetic Testing for Human Leukocyte Antigens (HLA)
Preimplantation Genetic Testing for Human Leukocyte Antigens (PGT-HLA) provides patients with an option not only to avoid an inherited risk when combined with single gene testing (PGT-M), […]
Interpreting Your RGI PGT-A Results
Your report will include a summary of results for each embryo biopsy sample submitted for testing. The first number in the report represents the total chromosome count, followed by sex chromosomes, followed by abnormality or normal chromosome count.
Extracting the Story of You
Deoxyribonucleic acid (or DNA) is the chemical novel of you. A little less than half of your story comes from a paternal inheritance (for some people this […]
What is Non-Disclosure Preimplantation Genetic Testing
As the title states, non-disclosure involves keeping the at-risk individual’s status for a condition such as Huntington disease, for example, unknown. How can this be done, you may ask?
The Alphabet Soup of PGT
Throughout your pre-implantation testing journey, you might hear terms like PGT-A, PGT-M, PGT-SR, PGT-HLA, NGS, PCR, etc. All these letters can get pretty confusing if you aren’t sure what they mean, so let’s break it down.
A Brief History of Carrier Screening and Implications for a PGT-M Referral
Pan-ethnic carrier screening is replacing ethnicity-based carrier screening for single gene disorders For 50 years, identifying heterozygotes has made possible prevention of selected autosomal recessive disorders. If […]
Genetic Carrier Screening and Prenatal Genetic Diagnosis Extends to Adult Onset Disorders
Screening is now pan-ethnic, and uses DNA platforms. Couples of mixed ethnicities are screened without regard to specific ethnicity. Over 400 disorders can be screened, identifying approximately 2% at-risk couples.
Decreasing the Twin Rates in Assisted Reproductive Technologies (ART)
RGI recommends Preimplantation Genetic Testing for aneuploidy (PGT-A). Biopsy of a 5-6 day blastocyst can be performed before or after cryopreservation . PGT-A will reveal the chromosomal status of each embryo, allowing a single euploid embryo to be selected.
PGT for Inherited Heart Disease
According to the CDC, heart disease is the leading cause of death in the US. We all know our family medical history is very important. We know […]