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Throughout your pre-implantation testing journey, you might hear terms like PGT-A, PGT-M, PGT-SR, PGT-HLA, NGS, PCR, etc. All these letters can get pretty confusing if you aren’t sure what they mean, so let’s break it down. 

Patients ask us all the time if they should get a specific insurance since RGI is in-network with them. We remind them that we are just one piece of the puzzle. Patients have to keep in mind the overall cost of this whole process. The list below should be taken into consideration while evaluating your options for new insurance.

PGT-M is a genetic testing technique designed to identify if there is a single-gene disorder(s) in embryos created through in vitro fertilization (IVF). These disorders, which include conditions such as cystic fibrosis, sickle cell anemia, and Huntington’s disease, are usually caused by mutations in a single gene. By testing embryos for these genetic abnormalities before implantation, couples can select and transfer only those embryos that are free from the targeted disorder (genetic variant), avoiding the risk of passing it on to their children.

Preimplantation Genetic Testing for Human Leukocyte Antigens (PGT-HLA) provides patients with an option not only to avoid an inherited risk when combined with single gene testing (PGT-M), but also to establish a pregnancy with an exact HLA match to benefit an affected family member.

Your report will include a summary of results for each embryo biopsy sample submitted for testing. The first number in the report represents the total chromosome count, followed by sex chromosomes, followed by abnormality or normal chromosome count.

Deoxyribonucleic acid (or DNA) is the chemical novel of you.  A little less than half of your story comes from a paternal inheritance (for some people this […]

As the title states, non-disclosure involves keeping the at-risk individual’s status for a condition such as Huntington disease, for example, unknown. How can this be done, you may ask?

Having enough frozen specimens to complete your IVF cycles is a positive thing. Not all patients are able to produce or purchase the specimens they need to […]

Pan-ethnic carrier screening is replacing ethnicity-based carrier screening for single gene disorders For 50 years, identifying heterozygotes has made possible prevention of selected autosomal recessive disorders. If […]

Screening is now pan-ethnic, and uses DNA platforms. Couples of mixed ethnicities are screened without regard to specific ethnicity. Over 400 disorders can be screened, identifying approximately 2% at-risk couples.

In the world of Preimplantation Genetic Testing (PGT), we begin with an embryo biopsy. The quality of the biopsy is not always the same, in order to […]